VEGF gene polymorphisms and as a potential roles of bladder cancer recurrence factor

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Abstract

The study explores how certain variations in the VEGF (vascular endothelial growth factor) gene may influence the recurrence of bladder cancer, shedding light on its development and prognosis. Bladder cancer, mainly urothelial carcinoma, is complex and unpredictable, posing challenges for treatment. Understanding genetic factors, like VEGF gene variations, can help tailor treatment plans for better outcomes. The study highlights various pathways involved in bladder cancer progression, including the role of VEGF beyond just blood vessel growth. While some research suggests a connection between VEGF gene variations and bladder cancer risk, results vary. Identifying thesevariations could lead to personalized treatments and targeted therapies. However, more research is needed to understand how these genetic factors specifically affect cancer recurrence. Collaborative efforts and advanced studies are essential for improving bladder cancer management and patient outcomes.

About the authors

G. P. Siregar

Doctoral Study Program, Faculty of Medicine, Universitas Padjadjaran; Division of Urology, Department of Surgery, Faculty of Medicine, Universitas Sumatera Utara

Author for correspondence.
Email: ginandaputra@gmail.com

Ginanda Putra Siregar.

Bandung; Medan

Indonesia

I. Parwati

Department of Clinical Pathology, Faculty of Medicine, Universitas Padjadjaran

Email: idaparwati2008@gmail.com

Ida Parwati.

Bandung

Indonesia

F. Safridai

Department of Urology, Faculty of Medicine, Universitas Padjadjaran

Email: safriadif@yahoo.com

Ferry Safridai.

Bandung

Indonesia

T. Tjahjodjati

Department of Urology, Faculty of Medicine, Padjadjaran University, Hasan Sadikin Hospital

Email: tjahjodjati@yahoo.com

Tjahjodjati Tjahjodjati.

Bandung

Indonesia

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