Sentinel lymph node biopsy during radical prostatectomy in patients with prostate cancer: literature review

A. A. Izmailov; Измайлов А. А.; A. B. Chaprak; Чапрак А. Б.; Airat I. Garifullin; Гарифуллин Айрат Ильдарович; A. A. Izmailov; Измайлов А. А.; A. R. Khasiev; Хазиев А. Р.; A. R. Farganov; Фарганов А. Р.; T. Kh. Akchulpan; Акчулпан Т. Х.; K. Sh. Gantsev; Ганцев К. Ш.; T. G. Yatsenko; Яценко Т. Г.; Yu. N. Khrizman; Хризман Ю. Н.

doi:10.17650/1726-9776-2025-21-4-162-168

Sentinel lymph node biopsy during radical prostatectomy in patients with prostate cancer: literature review

Authors: Izmailov A.A.¹^,2, Chaprak A.B.¹, Garifullin A.I.¹, Izmailov A.A.³, Khasiev A.R.¹, Farganov A.R.¹, Akchulpan T.K.¹, Gantsev K.S.¹^,2, Yatsenko T.G.¹, Khrizman Y.N.¹
Affiliations:
1. Republican Clinical Oncology Dispensary, Ministry of Health of the Republic of Bashkortostan, Ufa
2. Bashkir State Medical University, Ministry of Health of Russia
3. Moscow City Oncology Hospital No. 62, Moscow Healthcare Department
Issue: Vol 21, No 4 (2025)
Pages: 162-168
Section: REVIEWS
Published: 27.02.2026
URL: https://oncourology.eco-vector.com/oncur/article/view/1927
DOI: https://doi.org/10.17650/1726-9776-2025-21-4-162-168
ID: 1927

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Abstract

Prostate cancer is one of the most frequently diagnosed oncological diseases worldwide and in the Russian Federation. Modern extended pelvic lymph node dissection is the most reliable method for detecting metastases in regional lymph nodes in patients with prostate cancer. However, this method is associated with certain risks both during the operation and in the postoperative period, which encourages researchers to develop alternative diagnostic approaches. One such alternative is sentinel lymph node biopsy, which demonstrates high potential in diagnostics. At the same time, a number of factors must be considered: limited number of randomized clinical trials, diversity of protocols used, variability of radioisotope and tracer combinations, as well as the need to consider both instrumental and clinical data. For the widespread implementation of this approach in clinical practice, further scientific research is required, including studies conducted in Russia.

Keywords

prostate cancer, sentinel lymph node biopsy, radical prostatectomy, pelvic lymphadenectomy, radionuclide imaging

References

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Sentinel lymph node biopsy during radical prostatectomy in patients with prostate cancer: literature review

Full Text

Abstract

Keywords

About the authors

References

Supplementary files