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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Cancer Urology</journal-id><journal-title-group><journal-title xml:lang="en">Cancer Urology</journal-title><trans-title-group xml:lang="ru"><trans-title>Онкоурология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-9776</issn><issn publication-format="electronic">1996-1812</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1926</article-id><article-id pub-id-type="doi">10.17650/1726-9776-2025-21-3-130-135</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CLINICAL NOTES</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ СЛУЧАИ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">A rare case of late progression of bladder cancer to the pubic bone without regional progression after 12 years</article-title><trans-title-group xml:lang="ru"><trans-title>Редкий случай позднего прогрессирования рака мочевого пузыря в лонную кость без регионарного метастазирования через 12 лет</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8676-2932</contrib-id><name-alternatives><name xml:lang="en"><surname>Khakimov</surname><given-names>K. I.</given-names></name><name xml:lang="ru"><surname>Хакимов</surname><given-names>Х. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>khurshed.1319@gmail.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3882-4665</contrib-id><name-alternatives><name xml:lang="en"><surname>Anisenya</surname><given-names>I. I.</given-names></name><name xml:lang="ru"><surname>Анисеня</surname><given-names>И. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>khurshed.1319@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7127-0188</contrib-id><name-alternatives><name xml:lang="en"><surname>Usynin</surname><given-names>E. A.</given-names></name><name xml:lang="ru"><surname>Усынин</surname><given-names>Е. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>khurshed.1319@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0829-0340</contrib-id><name-alternatives><name xml:lang="en"><surname>Chernyakov</surname><given-names>A. A.</given-names></name><name xml:lang="ru"><surname>Черняков</surname><given-names>А. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>khurshed.1319@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6309-2000</contrib-id><name-alternatives><name xml:lang="en"><surname>Bogoutdinova</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Богоутдинова</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>khurshed.1319@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0674-2067</contrib-id><name-alternatives><name xml:lang="en"><surname>Sitnikov</surname><given-names>P. K.</given-names></name><name xml:lang="ru"><surname>Ситников</surname><given-names>П. К.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>khurshed.1319@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4066-2688</contrib-id><name-alternatives><name xml:lang="en"><surname>Vasiliev</surname><given-names>N. V.</given-names></name><name xml:lang="ru"><surname>Васильев</surname><given-names>Н. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>khurshed.1319@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Cancer Research Institute – branch of the Tomsk National Research Medical Center of the Russian Academy of Sciences</institution></aff><aff><institution xml:lang="ru">Научно-исследовательский институт онкологии – филиал ФГБНУ «Томский национальный исследовательский медицинский центр Российской академии наук»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Siberian State Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Сибирский государственный медицинский университет» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-12-18" publication-format="electronic"><day>18</day><month>12</month><year>2025</year></pub-date><volume>21</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>130</fpage><lpage>135</lpage><history><date date-type="received" iso-8601-date="2025-03-31"><day>31</day><month>03</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-10-15"><day>15</day><month>10</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Khakimov K.I., Anisenya I.I., Usynin E.A., Chernyakov A.A., Bogoutdinova A.V., Sitnikov P.K., Vasiliev N.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Хакимов Х.И., Анисеня И.И., Усынин Е.А., Черняков А.А., Богоутдинова А.В., Ситников П.К., Васильев Н.В.</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Khakimov K.I., Anisenya I.I., Usynin E.A., Chernyakov A.A., Bogoutdinova A.V., Sitnikov P.K., Vasiliev N.V.</copyright-holder><copyright-holder xml:lang="ru">Хакимов Х.И., Анисеня И.И., Усынин Е.А., Черняков А.А., Богоутдинова А.В., Ситников П.К., Васильев Н.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://oncourology.eco-vector.com/oncur/article/view/1926">https://oncourology.eco-vector.com/oncur/article/view/1926</self-uri><abstract xml:lang="en"><p>Bladder cancer occupies a significant place among all malignancies, accounting for approximately 3 % of all new cases of malignancy per year, with approximately 37 % of all bladder cancer cases being fatal (about 213,000 deaths annually). Despite advances in diagnosis and treatment, patients with muscle-invasive cancer remain at high risk for recurrence and metastases, especially delayed metastases that may occur years after completion of primary treatment. These delayed metastatic manifestations are often associated with poor prognosis and treatment difficulties. This article presents a clinical case of late progression of bladder cancer to the left pubic bone without regional metastases 12 years after combination treatment.</p></abstract><trans-abstract xml:lang="ru"><p>Рак мочевого пузыря занимает значительное место среди всех злокачественных опухолей, на него приходится около 3 % всех новых случаев онкологических заболеваний в год. Примерно 37 % от общего числа случаев рака мочевого пузыря заканчиваются летальным исходом (около 213 тыс. смертей ежегодно). Несмотря на успехи в диагностике и лечении, пациенты с мышечно-инвазивным раком остаются в группе высокого риска развития рецидивов и метастазов, особенно отсроченных, которые могут возникнуть спустя годы после завершения первичного лечения. Эти отсроченные метастатические проявления часто ассоциируются с неблагоприятным прогнозом и сложностями в лечении. В данной публикации представлен клинический случай позднего прогрессирования рака мочевого пузыря в левую лонную кость без регионарных метастазов через 12 лет после комбинированного лечения.</p></trans-abstract><kwd-group xml:lang="en"><kwd>bladder cancer</kwd><kwd>progression</kwd><kwd>pelvic bones</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак мочевого пузыря</kwd><kwd>прогрессирование</kwd><kwd>кости таза</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">нет</funding-statement></funding-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">State of oncological care in Russia in 2022. Eds.: А.D. Kaprin, V.V. Starinskiy, A.O. Shachzadova. Moscow: MNIOI im. P.A. Gertsena – filial FGBU “NMITS radiologii” Minzdrava Rossii, 2022. 239 p. (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Состояние онкологической помощи населению России в 2022 году. Под ред. А.Д. Каприна, В.В. 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